The 3D structures of peptides and proteins and their structure-activity relationship studies provide valuable information for the design of synthetic molecules that mimic key determinants involved in protein−protein interactions. We perform biophysical studies on lead peptides and the active analogues using 2D-1H NMR and computer assisted molecular modeling techniques.
- Random Coil Chemical Shifts for backbone Atoms
- Secondary Structure
- Docking Studies
- Physicochemical Studies using Pipeline Pilot